Tuesday, December 23, 2025
Home Blog Page 649

Study Finds Opioid Users Not Switching To Medical Marijuana

Ever since it was revealed a few years back that prescription painkiller use was down in states where medical marijuana was legal, there has been some hope cannabis might be part of the solution to the opioid epidemic. So much, in fact, that some states, like Illinois and New York, have even passed laws in recent months allowing patients to use medical cannabis as a substitute for painkillers. But a study finds opioids users not switching to medical marijuana.

But is there really any truth to the idea that marijuana could be a saving grace for the tens of thousands of people who die every year as a result of opioid overdose?

According to researchers at Columbia University, probably not. They have found that while more Americans are using medical marijuana these days than ever before, they are also popping more, not less, opioid drugs. And they are not just using these medications as directed by a physician, but misusing them in ways that could lead them down a dark path to addiction and put them at risk for an overdose.  

RELATED: The Opioid Crisis Is Not About Pain

The study, which was based on an analysis of 70,000 U.S. citizens aged 12 and up, shows that hardcore opioid users are not the ones gravitating towards medical marijuana as an alternative to their vice.  

These people are also not at any lower risk of succumbing to a deadly overdose. 

In other words, people out there using heroin or even engaging in the recreational use of pain pills are not likely going to be saved with medical marijuana. 

“Other studies that found an inverse association between medical marijuana enactment and opioid-outcomes did not measure opioid-outcomes for individuals,” lead researcher Dr. Silvia Martins told The Daily Mail

This is not the first time research has shown that medical marijuana may not be a salvation’s wing for the opioid problem.

RELATED: Why Cannabis Is Better Than Opioids

A recent study from Stanford University shows that opioid overdose deaths have actually increased in states with medical marijuana laws on the books. The study shocked and even silence a lot of the cannabis community. Some advocacy zealots have even chosen to completely disregard the findings.

But what makes this piece of research so credible is it is based on the same methods as the highly-cited University of Pennsylvania study from 2014 showing opioid reductions in medical marijuana states. The consensus among Stanford researchers is that while there may have been a decrease in opioid prescriptions between 1999-2010, the narrative changed drastically over the past decade.  

“If you believed the results of the first study, it’s hard to argue that you don’t believe the results of the second one, since the methods are the same,” Chelsea Shover, a postdoctoral researcher at Stanford, told The Atlantic.

RELATED: Maybe Medical Marijuana Isn’t The Opioid Epidemic Savior After All

But it’s not all bad news for medical marijuana. Researchers at Columbia say that although it seems unlikely that cannabis can save people ravaged by the grips of opioid addiction, it might be able to stop more of them from going down that path. It is conceivable, they say, that if medicinal cannabis is prescribed as part of a pain management program from day one that many patients may never need to experience opioids in the first place. So instead of a trapdoor out of opioid addiction, maybe we should be looking at cannabis as a preventative measure, researchers said. 

‘Our findings may suggest that medical marijuana policies could be insufficient to reduce individual-level opioid outcomes and that opioid-specific approaches and policy interventions such as prescription drug monitoring programs, and laws on prescribing practices are needed,’ Martins said.

Chrissy Metz Says She Met Her Boyfriend on Instagram; Where Meghan Markle And Kate Middleton’s Relationship Stands Now

Where Meghan Markle and Kate Middleton’s Relationship Stands Now

Via Entertainment Tonight:

Following months of constant rumors of tension between the two, Meghan Markle and Kate Middleton appear to be closer than ever, with new reports claiming that the Duchess of Sussex and Duchess of Cambridge have strengthened their relationship.

Royal expert Katie Nicholl tells ET that the royals’ latest outings together will “hopefully put to rest the rumors that Kate and Meghan don’t get along because they certainly look like two duchesses who had plenty in common.”

https://www.instagram.com/p/Bz3JmeTlcpN

“There have been two major circumstances, which are very calculated and deliberate efforts to try and stem these rumors about a feud between the foursome,” Nicholl says of Kate, Meghan and husbands Prince William and Prince Harry. “We saw it at the polo match where William and Harry were obviously playing together. We hadn’t expected the duchesses to turn up with their children. The fact that they did is a wonderful treat for royal watchers, but I think those candid pictures were quite deliberately intended to snuff out those rumors of the feud between the foursome. And you saw them all very close, very happy, very comfortable with each other.”

Royal fans were then treated to another outing between Kate and Meghan. The two, along with Kate’s sister, Pippa Middleton, attended Serena Williams’ Wimbledon match on Saturday.

“You’re going to be reading stories about how the duchesses get on and I am told that both of them are making an effort to get along,” Nicholl adds.

Chrissy Metz Says She Met Her Boyfriend on Instagram

Via People:

Chrissy Metz is once again proving the age-old saying to be true: “It all goes down in the DMs.”

The This Is Us actress swung by The Wendy Williams Show on Wednesday when she revealed that she has a new boyfriend she met via direct message on Instagram.

“I know, cute, right?” said Metz, 38. “As the kids say, ‘He slid into the DMs.’ “

“I get thankfully a lot of messages and I don’t always get to see them all,” Metz explained. “He had messaged a couple of times, very sweet but not obnoxious or weird. And then I was like, ‘Let me see if he’s cute. Oh, he’s cute! Okay, I guess I can respond.’ But I waited a little bit because you can’t be an eager beaver. And then I responded, and then we just sort of hit it off.”

“It’s a very new relationship. It’s very exciting,” Metz told Williams.

 

Sorry, But Science Doesn’t Favor Microdosing Psychedelics

Enough of us have at least heard of microdosing by now. And if you pressed hard enough, I’m sure most of us could sketch a rough outline of what microdsoing is and looks like. Something like, “A Silicon Valley trend that involves repeatedly ingesting small samples of psychedelic substances—though not enough to actually trip—to invoke cognitive and physical boosts.”

As a new paper published in the Journal of Psychopharmacology details, most of what we know around microdosing psychedelics stems from anecdotal evidence. A group of international researchers aimed to systematize and analyze some foundational questions around the phenomenon: What is the scientific definition of micrdosing? How does it work? Does it even work? Could it be harming or helping our bodies? Is it illegal? Answering these questions could provide a necessary framework to tackle more scientifically rigorous analysis around microdosing.

RELATED: How Melding Marijuana Microdosing And Kundalini Yoga Can Heal The Brain

“Despite so much interest in the subject, we still don’t have any agreed scientific consensus on what microdosing is — like what constitutes a ‘micro’ dose, how often someone would take it, and even if there may be potential health effects” said David Nutt, senior author of the paper and the Edmond J. Safra Chair in Neuropsychopharmacology at Imperial College London.

While the general public might be attracted to experimenting with microdosing after reading online testimonials and online articles, researchers stressed that microdosing isn’t so easy breezy. The team highlighted the possibility of cardiovascular risk caused by microdosing, as well as other studies that found negative persistent behavioral changes caused by taking LSD every other day over the course of several months.

But researchers also analyzed if the claims made by microdosing evangelists is plausible from a biological perspective. They referenced early-stage research that demonstrated how psilocybin can target receptors in the brain that binds to serotonin. Taken at small doses, it could be possible that binding with serotonin — which is a chemical messenger that typically coincides with sensations of joy, learning, and memory — would produce the so-called therapeutic effects reported by those who experienced it.

RELATED: 4 CBD Questions We Need Researchers To Answer ASAP

In addition, there is evidence that low doses of psychedelics could have a profound anti-inflammatory effect on peripheral tissues. Previous animal studies have shown how such properties can result in the reduction of allergic asthma and intestinal inflammation.

“It remains to be seen whether very low levels of psychedelics are also anti-inflammatory in humans, and if the anti-inflammatory activity also occurs in the brain, but if these findings do translate then levels typically used in microdosing regimes for some psychedelic compounds would be predicted to have significant and beneficial anti-inflammatory effects,” the authors wrote.

They also added that while LSD is considered one of the most powerful “mind-altering psychedelics,” it is among “the least potent anti-inflammatories tested.”

When Royal Offsprings Start Bowing To The Queen

Can you imagine having to bow every time you saw your grandparents? They’re the ones who notoriously spoil you, feed you junk food and slip you money when mom and dad aren’t looking. It’s hard to think of them as someone you need to curtsy to. But when you’re a royal, it’s common practice. At least by the time you’re in kindergarten. When does it change and so when royal offsprings start bowing to the Queen.

According to royal expert and blogger Marlene Eilers Koenig, age five is when royal children are expected to start bowing to Queen Elizabeth.

“Certainly by age five. The only person they will curtsy or bow to is the sovereign. A royal highness does not curtsy to another royal highness,” Koenig told Hello! Magazine in a 2018 interview.

RELATED: Here’s Why It’s Not Cool To Call The Queen ‘Her Royal Highness’

According to Koenig, this practice of bowing isn’t royal protocol, it’s simply royal etiquette.

“You bow or curtsy the first time you see the sovereign and then again when you leave,” she said. If you recall, it was a big deal when Meghan Markle, Prince Harry’s fiancé at the time, made her fist curtsy to the Queen during Christmas services 2017.

Koenig said the reason we didn’t see other royals, like Prince Charles, curtsy is because they come from another engagement and had already seen the Queen.

RELATED: Here’s One Thing You’ll Never See A British Royal Do

Prince George celebrates his sixth birthday on Monday, so he likely has already been bowing to his great-grandmother for a year. Charlotte has another year before she turns five. And, well, Louis and Archie are too young to even know what a curtsy is. And if Archie takes after his rule-breaking mom, who knows if he’ll buck tradition or fall in line like the other royal children.

Did Vikings Bring Marijuana To North America

Archaeologists excavating and analyzing a Viking settlement in Newfoundland found mostly what you might expect from such a dig: rare beetles, fossilized plants, and caribou dung. You know, the usual archaeology kind of stuff. But researchers also found one substance raising some high-minded questions — cannabis.

Published in the Proceedings of the National Academy of Sciences, researchers focused on L’Anse aux Meadows, a site in northern Newfoundland where Vikings landed and settled around the year 1000. Previously scientists believed Vikings only stayed in this spot a short time, but their work uncovered the possibility Vikings may have stayed until the 12th or 13th century. And they might have had marijuana with them.

RELATED: STUDY: How Cannabis Could Be Used To Curb Cannabis Addiction

An archaeological team excavated a peat bog about 100 feet from the Viking settlement back in August 2018. As Live Science reports, they found a layer of “ecofacts,” which are “environmental remains that may have been brought to the site by humans.” This layer was radiocarbon dated to the early Middle Ages and is where researchers discovered cannabis pollen, a plant not native to the area.

The question proposed here is what could Vikings have used cannabis for? Were they producing clothing from the plant’s fibers or smoking it for medical or potentially recreational reasons? It also could mean none of these things, reminded the study’s lead author and postdoctoral fellow at Memorial University of Newfoundland, Paul Ledger.

RELATED: Want To Survive A Heart Attack? Use Cannabis, Say Researchers

While it’s certainly fun imagining Vikings lighting up a spliff after a long day of barbarian activities, the cannabis pollen could just as easily have been carried by the wind and landed in the peat bog. It’s also possible humans local to the Newfoundland area and not Vikings could have been the ones responsible for the cannabis pollen. As the research team wrote in the paper, “the results presented here pose more questions than answers.”

Viking scholars — which, yes, is an awesome job — were dubious of the results, according to Live Science. They also mentioned the possibilities I wrote above. But Ledger said researchers will return to the area and resume their work this August. And if they find rolling papers in the bog this time, then we’ll know for real the Vikings were up to something.

5 Videos Of Cute Animals To Get You Through This Week: July 15

Instagram is home to all sorts of accounts (good and bad) that cater to a vast range of people with different interests. In order to help you weed out all the garbage, this column highlights the best Instagram marijuana accounts, whether that means they’re entertaining, informative, or just fun to look at.

This week’s column is all about cats and dogs. There’s a cat confused by its own reflection, a cat who’s snuggled in a sink, a dog whose owners think he’s the Lion King, a dog inside a box, and a dog being scratched by four different scratchers. Check them out!

A cat and a mirror

https://www.instagram.com/p/BzyG5Ehotei/

RELATED: 5 Videos Of Cute Animals To Get You Through This Week: July 8

Videos of animals freaking out over their own reflections never get old, with this one in particular having a special charm over how dramatic the cat is.

A cat inside a sink

https://www.instagram.com/p/Bz8Qo9lgUAQ/

Cats love boxes, sinks and small spaces that keep them snuggled. This cat is giving himself a bath but looks spooked over the prospect of being splashed with real water.

The Lion King

https://www.instagram.com/p/B0BCTpOnWJa/

“The Circle of Life” is one of the most iconic songs of all time. Featured in The Lion King’s amazing opening, it’s also the moment where baby Simba is introduced to the world, just like the dog in the video. Kind of. At least he stays very still.

A puppy in a box

https://www.instagram.com/p/Bz-6x4MHRdz/

RELATED: 5 Videos Of Cute Animals To Get You Through This Week: June 24

Puppies don’t know how to bark, resulting in them making those adorable quasi-howling sounds. The little guy in this video has an Instagram account called @thatgoldenwaffle that features tons of adorableness.

A frenchie and four scratchers

https://www.instagram.com/p/Bz5yqQAAe-5/

This Frenchie looks more confused than pleased over being massaged in four different directions, looking at each of the scratchers and wondering what the hell they’re doing.

CBD Questions We Need Researchers To Answer

CBD research hasn’t quite caught up to the compound’s rapid rise in popularity. Experimentation in the lab is just beginning, putting consumers in the awkward position of knowing that the compound produces powerful therapeutic effects that remain shrouded in mystery. While it is proven to have done well, there are CBD questions we need researcher to answer.

Now that legalization is in full force and CBD is primed to become one of the largest industries in the U.S., it’s the perfect time for government, large companies and researchers find the data around some pressing questions about the compound.

How can we calculate the right dose of CBD?

https://giphy.com/gifs/character-presentation-animation-3o85xm0pDVY4EkKdFe

RELATED: 5 Ways To Incorporate Effective CBD Products Into Your Everyday Life

One of the biggest questions that plague CBD users is finding the right dosage in order to treat whatever is ailing them. There’s not much data or research on CBD available, making people rely on an estimate of how much they should consume with no consideration for their body type and experience with the drug. As long as there’s no data, there can be no accurate way of obtaining the right dosage, and people will continue to use trial and error as a way of self-medicating.

Does CBD’s consumption method have some effect?

https://giphy.com/gifs/i-dont-know-chris-farley-bPTXcJiIzzWz6

One of the best aspects of medical marijuana is the variety of consumption methods, which affect ailments in different ways. For example, for the treatment of muscle pains many doctors and experts recommend transdermal patches, which target the area more accurately over smoking flower. There’s no such knowledge on CBD, which can be vaped or consumed in an edible with no apparent difference for the pain or ailment that’s bothering people.

Does CBD interact with other cannabinoids?

https://giphy.com/gifs/chemistry-research-3fk0i2VKOX1TEZQbcJ

RELATED: How To: A Beginner’s Guide To Buying CBD Products

Cannabis compounds have a way of interacting with each other, altering the effect on our endocannabinoid system. While some studies say that, when consumed together, CBD makes THC less psychoactive and more therapeutic, not much else is known about it’s effect with other compounds. The few CBD studies that are being conducted tend to isolate the product. There’s also the fact that many companies are trying to sell it on their own as a wellness or beauty product, separating it from cannabis (mainly THC) and the possible controversies that surround it.

What are CBD’s real therapeutic effects?

https://giphy.com/gifs/nhl-brandon-saad-chicago-blackhawks-RIVs14HzS8Xn2

CBD is advertised as a sort of cure all medicine, which is great, but leaves us with a lot of questions and room for companies to take advantage of people and their lack of information. By labeling it a miracle drug, information about CBD remains vague and easy to manipulate. Once more research and data is acquired, users may finally learn CBD’s real properties and its true therapeutic capabilities.

Did We Mishear Neil Armstrong’s First Words On The Moon

On July 20, 1969, an estimated 650 million people watched in suspense as Neil Armstrong descended a ladder towards the surface of the Moon.

As he took his first steps, he uttered words that would be written into history books for generations to come: “That’s one small step for man. One giant leap for mankind.”

Or at least that’s how the media reported his words.

But Armstrong insisted that he actually said, “That’s one small step for a man.” In fact, in the official transcript of the Moon landing mission, NASA transcribes the quote as “that’s one small step for (a) man.”

As a linguist, I’m fascinated by mistakes between what people say and what people hear.

In fact, I recently conducted a study on ambiguous speech, using Armstrong’s famous quote to try to figure out why and how we successfully understand speech most of the time, but also make the occasional mistake.

Our extraordinary speech-processing abilities

Despite confusion over Armstrong’s words, speakers and listeners have a remarkable ability to agree on what is said and what is heard.

When we talk, we formulate a thought, retrieve words from memory and move our mouths to produce sound. We do this quickly, producing, in English, around five syllables every second.

RELATED: A Linguist’s View On The Way We Talk About Marijuana

The process for listeners is equally complex and speedy. We hear sounds, which we separate into speech and non-speech information, combine the speech sounds into words, and determine the meanings of these words. Again, this happens nearly instantaneously, and errors rarely occur.

These processes are even more extraordinary when you think more closely about the properties of speech. Unlike writing, speech doesn’t have spaces between words. When people speak, there are typically very few pauses within a sentence.

Yet listeners have little trouble determining word boundaries in real time. This is because there are little cues – like pitch and rhythm – that indicate when one word stops and the next begins.

But problems in speech perception can arise when those kinds of cues are missing, especially when pitch and rhythm are used for non-linguistic purposes, like in music. This is one reason why misheard song lyrics – called “mondegreens” – are common. When singing or rapping, a lot of the speech cues we usually use are shifted to accommodate the song’s beat, which can end up jamming our default perception process.

But it’s not just lyrics that are misheard. This can happen in everyday speech, and some have wondered if this is what happened in the case of Neil Armstrong.

Studying Armstrong’s mixed signals

Over the years, researchers have tried to comb the audio files of Armstrong’s famous words, with mixed results. Some have suggested that Armstrong definitely produced the infamous “a,” while others maintain that it’s unlikely or too difficult to tell. But the original sound file was recorded 50 years ago, and the quality is pretty poor.

 

So can we ever really know whether Neil Armstrong uttered that little “a”?

Perhaps not. But in a recent study, my colleagues and I tried to get to the bottom of this.

First, we explored how similar the speech signals are when a speaker intends to say “for” or “for a.” That is, could a production of “for” be consistent with the sound waves, or acoustics, of “for a,” and vice-versa?

So we examined nearly 200 productions of “for” and 200 productions of “for a.” We found that the acoustics of the productions of each of these tokens were nearly identical. In other words, the sound waves produced by “He bought it for a school” and “He bought one for school” are strikingly similar.

RELATED: JK: Why Sarcasm Is So Difficult To Detect In Texts And Emails

But this doesn’t tell us what Armstrong actually said on that July day in 1969. So we wanted to see if listeners sometimes miss little words like “a” in contexts like Armstrong’s phrase.

We wondered whether “a” was always perceived by listeners, even when it was clearly produced. And we found that, in several studies, listeners often misheard short words, like “a.” This is especially true when the speaking rate was as slow as Armstrong’s.

In addition, we were able to manipulate whether or not people heard these short words just by altering the rate of speech. So perhaps this was a perfect storm of conditions for listeners to misperceive the intended meaning of this famous quote.

The case of the missing “a” is one example of the challenges in producing and understanding speech. Nonetheless, we typically perceive and produce speech quickly, easily and without conscious effort.

A better understanding of this process can be especially useful when trying to help people with speech or hearing impairments. And it allows researchers to better understand how these skills are learned by adults trying to acquire a new language, which can, in turn, help language learners develop more efficient strategies.

Fifty years ago, humanity was changed when Neil Armstrong took those first steps on the Moon. But he probably didn’t realize that his famous first words could also help us better understand how humans communicate.

 

Harry’s Advice To Meghan Markle About Being A Royal Mom

It can’t be easy transitioning from a commoner to a member of the royal family. And even though the Duchess was less of a commoner than most of us before she married Prince Harry last May, the road to being a Duchess has been a bumpy one for the former Hollywood actress. The prince has tried to be helpful. An example is Prince Harry’s advice to Megan Markle about being a royal mom.

Harry is hugely supportive of his wife, even while she bucks protocol left and right, but according to a royal insider, Harry has recommended that Meghan “move with ease.”

RELATED: Meghan Markle Is Being Mom Shamed For Doing This In Public

“It’s hard for Meghan in London because the press is so vicious to her there,” the insider told US Weekly. “This is her life. But her mentality is like, ‘Well, if this is what it’s going to be like, I’m going to do what I want to do. I won’t play by these rules.’”

Meghan has been embroiled in judgment since she started dating Harry. Most recently, she was mom-shamed for the way she carried her baby at a charity polo match, how she dressed at Wimbledon, and how she can’t seem to keep a nanny because of “control issues.”

Prince Harry’s advice to Megan Markle is something she should consider. Fortunately, she does get to revisit her entertainment roots every now and then, which must help her feel a little more “normal.” Recently, she attended the London premier of “The Lion King” and got to hang a bit with Beyoncé and Jay-Z, who told her and Harry to “always make time for yourself.” Whether he was talking about individually or as a couple, we think it’s sound advice. And timely.

Data Shows Marijuana To Help Curb Cannabis Addiction

Previous studies have shown that both marijuana and CBD could be used as a potential exit drug out of opioid addiction, with other, less widely used options like buprenorphine and methadone also available for those struggling with opioid dependency. But for those with cannabis use disorder, the available strategies have been far more limited.

Now, an Australian study published Monday in JAMA Internal Medicine demonstrated that one substance that could potentially curb cannabis dependency is cannabis itself. This doesn’t mean patients should consume more marijuana or anything like that. Instead, Australian scientists used a cannabis-based medicine called nabiximols to provide the first evidence that “cannabinoid agonist medication” targeting receptors in your brain can diminish the rate of relapse.

In a series of experiments, researchers tested regular marijuana smokers with two different substances. One group was given nabiximols, which is a spray placed underneath your tongue and comprised of equal parts cannabidiol (CBD) and tetrahydrocannabinol (THC). The other group was given a placebo. The study found those on nabiximols smoked 18.6 less days than those on the placebo.

RELATED: Marijuana Makes You Paranoid? Study Suggests Your Genes Are To Blame

“We’ve never had the evidence before that medication can be effective in treating cannabis dependency—this is the first big study to show this is a safe and effective approach,” said Nicholas Lintzeris, Ph.D., the lead study author and addiction medicine specialist at the University of Sydney School of Medicine.

“The principles are very similar to nicotine replacement; you are providing patients with a medicine which is safer than the drug they’re already using, and linking this with medical and counselling support to help people address their illicit cannabis use,” he added.

Lintzeris said an important element of the study was recruiting only cannabis users who had previously attempted to lower their marijuana usage but could not on their own. Another key component was adding cognitive behavior therapy (CBT) as well as therapeutic support to elicit a more holistic approach.

Said Lintzeris, “Our study is an important step in addressing the lack of effective treatments—currently, four in five patients relapse to regular use within six months of medical or psychological interventions.”

Don't Miss Your Weekly Dose of The Fresh Toast.

Stay informed with exclusive news briefs delivered directly to your inbox every Friday.

We respect your privacy. Unsubscribe anytime.